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  • Biological Buffers 

    Be confident in protecting key therapeutic proteins from denaturization, ensure efficient stabilization of the product and get consistent performance with Avantor's broad range of biological buffers. Our biological buffers are available in a wide variety of product grades, and are specifically engineered for biotechnology, cell biology and molecular biology applications, including biopharmaceutical production

    • Nontoxic to cells 
    • Not absorbed through cell membranes  
    • Feature pKa values at or near physiological pH  
    • Reliably stabilize product as it goes through multi-step purification process 
    • Operate in a wide variety of pH ranges
    • Minimal effects on chromatographic separation 

    J.T.Baker® brand ULTRAPURE BIOREAGENT biological buffers and Macron Fine Chemicals™ brand GenAR biological buffers are characterized by high assay, low insolubles and heavy metals and the absence of DNase, RNase and protease. Our TRIS (tromethamine) is tested to USP specifications -- meeting USP requirements, EP specifications and additional stringent ULTRAPURE BIOREAGENT criteria. Our products are made in world-class cGMP-validated solutions facilities,  like our other pharmaceutical chemical products. 

    J.T.Baker® and Macron Fine Chemicals™ Brands Biological Buffers  

    Product Description 

    Product Number  

    CAPS 

    4118 

    CHES 

    4146 

    CHES, Sodium Salt 

    4147 

    Guanidine Hydrochloride 

    0072 

    Guanidine Hydrochloride 

    0506 

    Guanidine Hydrochloride 

    0507 

    Guanidine Hydrochloride 

    7716 

    HEPES, Free Acid 

    4018 

    HEPES, Sodium Salt 

    4153 

    MES, Monohydrate, Free Acid, Crystalline 

    4014 

    MOPS 

    4004 

    MOPS, Sodium Salt 

    4163 

    PIPES 

    4265 

    PIPES, Sodium Salt 

    4266 

    TRIS (Base) 

    4109 

    TRIS (Base) 

    4099 

    TRIS Hydrochloride 

    4103 

    TRIS Hydrochloride 

    4106